"Joe Palooka is a naive young man whose father Pete was a champion boxer, but his lifestyle caused Joe's mother Mayme to leave him and to take young Joe to the country to raise him."
Jimmy Durante
as Knobby Walsh
Lupe Vélez
as Nina Madero
Stuart Erwin
as Joe Palooka
Marjorie Rambeau
as Mayme Palooka
Thelma Todd
as Trixie
Robert Armstrong
as Pete Palooka
Mary Carlisle
as Anne Howe
William Cagney
as Al McSwatt
Franklyn Ardell
as Doc Wise
Tom Dugan
as Whitey
Louise Beavers
as Crystal
Fred 'Snowflake' Toones
as Smokey (as Snowflake)
Guinn 'Big Boy' Williams
as Slats (uncredited)
Benjamin Stoloff
Director
Edward Small
Producer
Grant Whytock
Editor
Murray Roth
Dialogue
Gertrude Purcell
Screenplay
Jack Jevne
Arthur Kober
Arthur Edeson
Director of Photography
Albert S. D'Agostino
Art Direction
Ben Ryan
Burton Lane
Songs
Harold Adamson
Lyricist